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Present Academic Rank and Title:
Dean of the School of Medicine
The Ford Foundation Professor of Medical Education
Professor, Department of Radiation Oncology
Professor, Department of Pediatrics Adjunct Professor,
Department of History
Medical Licensure:
National Board of Medical Examiners, 1980; Medical licenses in North Carolina, Kentucky, and Indiana
Specia
Multidisciplinary ClinicBreast
Research ProgramPrevention & Control
Clinical ExpertiseBrain Tumor
Breast Cancer
Radiation Oncology
Research InterestsEdward C. Halperin, M.D., M.A., is the author/editor of the fourth and fifth editions of Principles and Practice of Radiation Oncology, the first through fourth editions of Pediatric Radiation Oncology, and over 185 articles on the causes, prevention, and treatment of childhood cancer, adult central nervous system tumors, malignancies of the eye, and medical ethics and history. He is the Dean of the University of Louisville School of Medicine.
EducationCollege: 1971-1975
The Wharton School
University of Pennsylvania
Philadelphia, PA
B.S. in Economics, summa cum laude; Beta Gamma Sigma
Graduate: 1975-1979
School of Medicine
Yale University
New Haven, CT
M.D., cum laude; Alpha Omega Alpha
Graduate: 2002-2006
The Graduate School Duke University Durham, NC
M.A. in Liberal Studies
Professional Training and Academic Career:
2006 – present
Dean of the School of Medicine
The Ford Foundation Professor of Medical Education
Professor, Department of Radiation Oncology
Professor, Department of Pediatrics
Adjunct Professor, Department of History
University of Louisville
Louisville, KY
2002 to 2006
Vice Dean of the School of Medicine
Associate Vice Chancellor
The R.J. Reynolds Professor of Medical Education
Professor, Department of Radiation Oncology
Professor, Department of Pediatrics
Duke University Medical Center
Durham, NC
1998 to 2003
The L.R. Prosnitz Professor and Chairman
Department of Radiation Oncology
Professor
Department of Pediatrics
Chairman of the Finance and Audit Committee
Duke Faculty Practice Plan (1999-2002)
Duke University Medical Center
Durham, NC
1996 to 1998
Professor and Chairman
Department of Radiation Oncology
Professor
Department of Pediatrics
1994 to 1996
Vice-Chairman
Department of Radiation Oncology
1993 to 1996
Professor
Department of Radiation Oncology
Associate Professor
Department of Pediatrics
Duke University Medical Center
Durham, NC
1992-1993
Fellow, Center for Leadership Development
American Council on Education
Washington, DC
1990-1993
Associate Professor with tenure
Department of Radiation Oncology
Duke University Medical Center
Durham, NC
1987-1990
Associate Professor
Division of Radiation Oncology
Duke University Medical Center
Durham, NC
1983-1987
Assistant Professor
Division of Radiation Oncology
Duke University Medical Center
Durham, NC
1982-1983
Chief Resident in Radiation Medicine
Massachusetts General Hospital
Boston, MA
1980-1982
Resident in Radiation Medicine
Massachusetts General Hospital
Boston, MA
1979-1980
Intern in Internal Medicine
Stanford University Medical Center
Stanford, CA
Awards/Honors:
2007 Elected a member of the Kentucky Institute of Medicine.
2007 Distinguished Alumni Award, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School.
Listed in The Best Doctors in America 1994-1995, 1998-1999, 2001-2002, 2003-2004 Naifeh SW, editor. Aiken: Woodward/White Publishers 1994, 1998, 2001, 2003.
Silver Award (Highest Honor), Telly Award for Medical Movie Production for "Your Treatment with Radiation Therapy”, 2001.
Fellow, American College of Radiology, 1999.
1998 Silver Award from the Health Sciences Communications Association for video "Radiation Therapy for Kids".
1998 Best of Show - Medical Division; BCA Medical Education Award; Award of Excellence, all from the Biomedical Communications Association for video "Radiation Therapy for Kids".
1998 Bronze Certificate, International Association of Audio Visual Communicators, "Radiation Therapy for Kids", "International Cindy Competition".
1998 Honorable Mention, "Radiation Therapy for Kids", Columbus International Film Festival.
Award Winner, The Communicator Awards 1997 Video Competition for Television, Video, and Film Programs for "Radiation Therapy for Kids", 1997.
Listed in The 2000 Top Doctors in the U.S. and Canada. New York: MM Braun Publishing, in press, 1998.
Editor's Recognition Award, With Distinction, Radiology, 1996.
Listed in American Health Magazine, March 1996, on their list of "The Best Doctors in America".
Best medical education film, tools and techniques category, 1992, International Health and Film Festival for "Brachytherapy Safety, Part I".
Fellow, Center for Leadership Development, American Council on Education.
Travel Award of the American Society of Therapeutic Radiology and Oncology (1988).
Sigma Xi (1987).
American Cancer Society Clinical Oncology Career Development Award (1985-1988).
Resident's Award of the American Society of Therapeutic Radiology (1982).
American Cancer Society Clinical Fellowship (1982-1983).
Alpha Omega Alpha (1978).
Beta Gamma Sigma (1975).
Scott Foundation Award (1973).
PublicationsBooks:
1. Halperin EC, Kun LE, Constine LS, Tarbell NJ: Pediatric Radiation Oncology, New York: Raven Press, 1989.
2. Halperin EC, Constine LS, Tarbell NJ, Kun LE: Pediatric Radiation Oncology, Second Edition. New York: Raven Press, 1994.
3. Halperin EC, Constine LS, Tarbell NJ, Kun LE: Pediatric Radiation Oncology, Third Edition. Philadelphia: Lippincott Williams and Wilkins, 1999.
4. Publication in Russian: Halperin EC, Constine LS, Tarbell NJ, Kun LE: Pediatric Radiation Oncology, Second Edition. Moscow: Medistina Publishing Company, 1999.
5. Halperin EC (Associate Editor for the childhood cancer section) of Gunderson LL, Tepper JE: Clinical Radiation Oncology. New York: Churchill Livingstone, 2000.
6. Perez C, Brady L, Schmidt-Ulrich R, Halperin EC (editors): Principles and Practice of Radiation Oncology, Fourth edition. Philadelphia: Lippincott Williams and Wilkins, 2003.
7. Halperin EC, Constine LS, Tarbell NJ, Kun LE: Pediatric Radiation Oncology, Fourth Edition. Philadelphia: Lippincott Williams and Wilkins, 2004.
8. Halperin EC, Perez C, Brady L, (editors): Perez and Brady’s Principles and Practice of Radiation Oncology, fifth edition. Philadelphia: Lippincott Williams and Wilkins, 2007.
Publications in Refereed Journals:
1. Halperin EC, Thier SO, Rosenberg LE. The use of D-penicillamine in cystinuria: efficacy and side-effects. Yale J Biol Med, 54:439-446, 1981.
2. Halperin EC, Dosoretz DE, Goodman M, Wang CC. Radiotherapy of polymorphic reticulosis. Brit J Radiol, 55:645-649, 1982.
3. Meyer JE, Halperin EC, Linggood RM. Upper extremity lymph-angiography as an aid to treatment planning for stage IA epitrochlear Hodgkin's disease. Cardiovasc Interven Radiol, 5:279-280, 1982.
4. Halperin EC, Harisiadis L. The role of radiation therapy in metastatic renal cell carcinoma. Cancer, 51(4):614-617, 1983.
5. Halperin EC, Haas G, Dosoretz DE, Gitterman M, Barre HL, Cosimi AB, Suit HD. The immunologic effects of lymphoid irradiation in human and non-human primates: cellular changes and the potential for renal transplantation. Int J Rad Onc Biol Phys, 9:1083-1089, 1983.
6. Halperin EC, Greenberg M, Suit H. Sarcoma of bone and soft tissue following treatment of Hodgkin's Disease. Cancer, 53(2):232-236, 1984.
7. Haas G, Halperin EC, Dosoretz, DE, Barrett L, Jaffers, G., Delmonico FL, Suit H, Daggett WM, Russell PS, Cosimi AB. The effects of cyclosporine and lymphoid irradiation on allograft survival and peripheral blood T-cells. Heart Transplantation, 3(2):152-159, 1984.
8. Haas G, Halperin EC, Dosoretz DE, Linggood R, Russell PS, Colvin R, Barrett L, Cosimi AB. Differential Recovery of Circulating T-cell subsets after nodal irradiation for Hodgkin's disease. J Immunology, 132(2):1026-1030, 1983.
9. Meyer JE, Halperin EC, Levene SR, Stomper PC. Adrenal insufficiency secondary to metastatic lung carcinoma. J Comput Assist Tomography, 7(6):1107-1108, 1983.
10. Halperin EC, Delmonico F, Nelson P, Shipley WU, Cosimi AB. The use of local allograft irradiation following renal transplantation. Int J Rad Onc Biol Phys, 10:987-990, 1984.
11. Haas GS, Halperin EC, Dosoretz DE, Barrett L, Suit HD, Russell P, Cosimi AB. Prolonging the immunosuppressive effects of lymphoid irradiation by suppression of T-cell recovery prior to organ transplantation. Trans Proceed, 17(1):1294-1298, 1985.
12. Halperin EC. Total lymphoid irradiation as an immunosuppressive agent for organ transplantation and the treatment of autoimmune disease: A review. Clinical Radiology, 36:125-130, 1985.
13. Halperin EC. Pediatric brain stem tumors: Patterns of treatment failure and their implications for radiotherapy. Int J Rad Onc Biol Phys, 11:1293-1298, 1985.
14. Friedman HS, Burger PC, Bigner SH, Trojanowski JQ, Wikstrand CJ, Halperin EC, Bigner DD: Establishment and characterization of the human medulloblastoma cell line and transplantation xenograft D283 MED. J Neuropathology and Experimental Neurology, 44(6):592-605, 1985.
15. Halperin EC, Burger P. Conventional external beam radiotherapy for CNS malignancies. Neurologic Clinics, 3:867-882, 1985.
16. Halperin EC. Pediatric radiation oncology. Investigative Radiology, 21(5):429-436, 1986.
17. Hershatter BW, Halperin EC, Cox EB. Medulloblastoma: The Duke experience. Int J Rad Onc Biol Phys, 12:1771-1777, 1986.
18. Knechtle SJ, Halperin EC, Murphy CE, Saad T, Abernethy K, Miller D, Bollinger RR. The effect of cyclosporine, total lymphoid irradiation, and cobra venom factor on hyperacute rejection. J Heart Transplantation, 4(5):541-545, 1985.
19. Halperin EC, Cox EB. Radiation therapy in the management of neuroblastoma: The Duke University Medical Center experience 1967-1984. Int J Rad Onc Biol Phys, 12:1829-1837, 1986.
20. Knechtle SJ, Halperin EC, Bollinger RR. Xenograft survival in two species combinations using total lymphoid irradiation and cyclosporine. Transplantation, 43(2):173-175, 1987.
21. Malik RK, Friedman HS, Djang WT, Falletta JM, Buckley E, Kurtzberg J, Kinney TR, Stine K, Chaffee S, Hayes J, Halperin EC, Oakes WJ. Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide. Am J Ophthalmol, 102(2): 650-656, 1986.
22. Knechtle SJ, Halperin EC, Bollinger RR. Combined total lymphoid irradiation and cyclosporine promote xenograft survival. Transplantation Proceedings, 19(1)1137-1139, 1987.
23. Halperin EC. The right verb. Int J Rad Onc Biol Phys, 13:143, 1987.
24. Knechtle SJ, Halperin EC, Saad T, Bollinger RR. Prolonged cardiac xenograft survival using combined TLI and cyclosporine. J Heart Transplantation, 5(3):254-261, 1986.
25. Bullard D, Rawlings CE, Phillips B, Cox EB, Schold SC, Burger PC, Halperin EC. Oligodendroglioma: An analysis of the value of radiation therapy. Cancer, 60(9):2179-2188, 1987.
26. Halperin EC, Knechtle S, Abernethy K, Saad T, Miller D, Vernon WB, Bollinger RR. The influence of dose and dose rate of total lymphoid irradiation in the rat cardiac allograft model. Radiotherapy and Oncology, 9:311-318, 1987.
27. Halperin EC. Hepatic metastasis from neuroblastoma. Southern Med J, 80(11):1370-1374, 1987.
28. Halperin EC. Medical Origins of Duke University? N C Med J, 48(12):664-666, 1987.
29. Frantz FW, Terris DJ, Wyble CW, Halperin EC, Sanfilippo F, Scroggs MW, Honore G, Bollinger RR. Allogeneic small bowel transplantation with cyclosporine and donor whole body irradiation. Transplantation Proceedings, 20(1) Supp 1:193-196, 1988.
30. Friedman HS, Burger PC, Bigner SH, Trojanowski JQ, Brodeur GM, Wikstrand CJ, Kurtzberg J, Berens ME, Halperin EC, Bigner DD. Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc. Am J Pathology, 130(3):472-484, 1988.
31. Halperin EC. Desegregation of hospitals and medical societies in North Carolina. New Engl J Med, 318:58-63, 1988.
32. Halperin EC, Burger PC, Bullard DE. The fallacy of the localized supratentorial malignant glioma. Int J Rad Onc Biol Phys, 15:505-509, 1988.
33. Werner MH, Burger PC, Heinz ER, Friedman AH, Halperin EC, Schold Jr. SC. Intracranial atherosclerosis following radiotherapy. Neurology, 38:1158-1160, 1988.
34. Halperin EC, Fraser RW, Hughes J. The management of clinically localized prostate cancer: a summary of the consensus statement of the National Institutes of Health. N C Med J, 49: 75-79, 1988.
35. Halperin EC. The audition elective. Int J Rad Onc Bio Phys, 15:791-792, 1988.
36. Halperin EC, Bollinger RR. The role of irradiation in solid organ transplantation. Int J Rad Onc Bio Phys, 15:979-988, 1988.
37. Kliggerman AD, Halperin EC, Erexson GL, Honore G, Westbrook-Collins B, and Allen JW. A cytogenetic comparison of the responses of mouse and human peripheral blood lymphocytes to 60Co gamma radiation. Rad Research, 115:334-346, 1988.
38. Halperin EC. X-rays at the bar, 1896-1910. Investigative Radiology, 23(8):639-646, 1988.
39. Longee DC, Friedman HS, Djang WT, Halperin E, D'Souza BJ, Schold Jr. SC, Falletta JM, Oakes WJ. Transient late Magnetic Resonance Imaging changes suggesting progression of brain stem glioma: Implications for entry criteria for phase II trials. Neurosurgery, 23:248-253, 1988.
40. Halperin EC. The right to privacy and the duty to protect. Southern Med Journal, 81(10):1286-1290, 1988.
41. Halperin EC. George Bush, Michael Dukakis, and Health Policy Issues in the 1988 Presidential Campaign. N C Med J, 49(9):433-440, 1988.
42. Halperin, EC. A Doctor Interviews the Candidates for Governor. N C Med J, 49(9):423-428, 1988.
43. Friedman HS, Schold Jr. SC, Djang WT, Kurtzberg J, Longee DC, Halperin EC, Falletta JM, Coleman RE, Oakes WJ. Criteria for termination of phase II chemotherapy for patients with progressive or recurrent brain tumor. Neurology, 38:62-66, 1989.
44. Halperin EC, Wehn SM, Scott JW, Djang W, Oakes WJ, Friedman HS. Selection of a management strategy for pediatric brain stem tumors. Med and Ped Oncology, 17:116-125, 1989.
45. Erexson GL, Kligerman AD, Halperin EC, Honore G, Allan JW. Micronuclei in binucleated lymphocytes following exposure to cobalt 60 gamma radiation. Environmental and Molecular Mutagenesis, 13:128-132, 1989.
46. Suvarnamani C, Halperin EC, Proia A, Klintworth GK. The effects of total lymphoid irradiation upon corneal vascularization in the rat following chemical cautery. Radiation Res, 117:259-272, 1989.
47. Harland, RC, Halperin, EC, Yamaguchi, Y, Wyble, C, Bollinger, RR. Total lymphoid irradiation and cyclosporine prolongs cardiac allograft survival in the sensitized rat model. Transplant Proceedings, 21(1):1118-1119, 1989.
48. Halperin, EC. Consent for a minor's abortion. NC Med J, 50(4):214-215, 1989.
49. Friedman HS, Schold Jr. SC, Mahaley Jr. MS, Colvin OM, Oakes WJ, Vick NA, Burger PC, Bigner SH, Borowitz M, Halperin EC, Djang W, Falletta JM, DeLong R, Garvin JH, DeVivo DC, Norris D, Golumbe B, Winter J, Boziner RA, Sipahi H, Bigner DD. Phase II treatment of medulloblastoma and pinealoblastoma with melphalan: clinical therapy based on experimental models of human medulloblastoma. J Clin Oncol, 7(7):904-911, 1989.
50. Halperin EC, Bentel G, Heinz ER, Burger PC. Radiation therapy treatment planning in supratentorial glioblastoma multiforme: an analysis based on post mortem topographical analysis with CT correlation. Int J Rad Onc Biol Phys, 17:1347-1350, 1989.
51. Yamaguchi Y, Halperin EC, Harland RC, Wyble C, Bollinger RR. Significant prolongation of hamster liver transplant survival in Lewis rats by total lymphoid irradiation, cyclosporine, and splenectomy. Transplantation, 49(1):13-17, 1990.
52. Halperin EC, Morrow ST. Reducing infant mortality in North Carolina. NC Med J, 50(8):419-420, 1989.
53. Yamaguchi Y, Halperin EC, Harland RC, Wyble C, Bollinger RR. A synergistic effect of total lymphoid irradiation, cyclosporine, and splenectomy in a hamster-to-rat xenograft model. Transplantation Proceedings, 21(3):3556, 1989.
54. Weaver JP, Bobbitt Jr JD, Halperin EC. The model health care provider liability reform act: a summary and commentary. NC Med J, 49(12):621-624, 1988.
55. Lippitz BE, Halperin EC, Griffith OW, Colvin OM, Honore G, Osertag CB, Bigner DD, Friedman HS: L-Buthionine-Sulfoximine mediated radiosensitization in experimental interstitial radiotherapy of intracerebral D-54 mg glioma xenografts in athymic mice. Neurosurgery, 26(2):255-260, 1990.
56. Halperin EC. Physician awareness of the contents of the Hippocratic Oath. J of Med Humanities, 10(2):107-114, 1989.
57. Halperin EC. The North Carolina Medical Journal and its peers. NC Med J, 51(1):23-25, 1990.
58. Halperin EC, Knechtle SJ, Harland RC, Yamaguchi Y, Sontag M, Bollinger RR. Irradiation for Xenogeneic Transplantation. Radiotherapy and Oncol, 18:29-37, 1990.
59 Halperin EC. Informed consent for AIDS testing, Or: Whose vein is it anyway? NC Med J, 51(4):145-149, 1990.
60. Kligerman AD, Halperin EC, Erexson GL, and Honore G. The persistence of lymphocytes with dicentric chromosomes following whole body x-irradiation of mice. Rad Research, 124:22-27, 1990.
61. Halperin EC. The journal interviews State Legislative Leaders. NC Med J, 51(4): 172-177, 1990.
62. Halperin EC. Frank Porter Graham, Isaac Hall Manning, and the Jewish Quota at the University of North Carolina Medical School. NC Historical Review, 67(4):385-410, 1990.
63. Green DM, Samulski TV, Vervaert C, Halperin EC, Oleson JR, Seigler H. Effects of hyperthermia and irradiation on the growth of mouse melanoma tumors following immunotherapy. J Surg Oncol, 44:256-259, 1990.
64. Halperin EC. Doublespeak in high places. NC Med J, 51(8):393-396, 1990.
65. Halperin EC. A groundless hypothesis, megaloblastic madness, and the founding of Duke University. Med Hypotheses, 36:200-203, 1991.
66. Pruitt SK, Halperin EC, Bollinger RR. The effect of 15-deoxyspergualin on hamster-to-rat cardiac xenograft survival. Transplantation Proceedings, 23:585-586, 1991.
67. Bollinger RR, Fabian MA, Harland RC, Murray WJ, Baldwin WM, Abernethey K, Britt L, Sontag M, Halperin EC. Total lymphoid irradiation for cardiac xenotransplantation in non-human primates. Transplantation Proceedings, 23:587-588, 1991.
68. Bentel GC, Halperin EC. High-dose areas are unintentionally created as a result of gap shifts when the prescribed dose in the two adjacent areas are different. Med Dosimetry, 15:179-183, 1990.
69. Yamaguchi Y, Halperin EC, Mori K, Misumi M, Katsumori T, Takata N, Goto M, Makino Y, Kikuchi N, Takahashi K, Bollinger RR. Macrophage migration into hepatic xenografts in the hamster-to-rat combination. Transplantation Proceedings, 23(1):220-221, 1991.
70. Freeman CR, Krischer J, Sanford RA, Cohen M, Burger PC, Kun L, Halperin EC, Crocker I, Wharam M. Hyperfractionated radiotherapy in brain stem tumors. Results of treatment at the 7020 cGy dose level of Pediatric Oncology Group Study #8495. Cancer, 68:474-481, 1991.
71. Jones RB, Shpall EJ, Shogan J, Affronti ML, Coniglio D, Hart L, Halperin E, Iglehart JD, Moore J, Gockerman J, Bast RC, Peters WP. The Duke AFM Program: Intensive induction chemotherapy for metastatic breast cancer. Cancer, 66:431-436, 1990.
72. Halperin EC. Suspicionless drug testing of physicians. NC Med J, 52(4):131-135, 1991.
73. Scroggs MW, Proia AD, Smith CF, Halperin EC, Klintworth GK. The effect of total body irradiation upon corneal neovascularization in the Fischer 344 rat after chemical cauterization. Invest Opthalmol, Vis Sci, 32(7):2105-2111, 1991.
74 Griebel M, Friedman HS, Halperin EC, Wiener MD, Marks L, Oakes WJ, Hoffman JM, DeLong GR, Schold SC, Hockenberger B, Freeman C, Kun L. Reversible neurotoxicity following hyperfractionated radiation therapy of brain stem glioma. Med Pediat Oncol, 19:182-186, 1991.
75. Erexson GL, Kligerman AD, Bryant MF, Sontag MC, Halperin EC. Induction of micronuclei by x-irradiation in human, mouse, and rat peripheral blood lymphocytes. Mutation Res, 253:193-198, 1991.
76. Kavanagh BD, Halperin EC, Rosenbaum LC, Shannon EM, Nilaver G. Syndrome of inappropriate secretion of antidiuretic hormone in a patient with carcinoma of the nasopharynx. Cancer, 69(6):1315-1319, 1992.
77. Hoffman JM, Hanson MW, Friedman HS, Hockenberger BM, Oakes WJ, Halperin EC, Coleman RE. FDG-PET in pediatric posterior fossa brain tumors. J of Computer Assisted Tomography, 16(1):62-68, 1992.
78. Halperin EC, Brizel DM, Honore G, Sontag MR, Griffith OW, Bigner DD, Friedman HS. The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine. Int J Rad Onc Biol Phys, 24:103-109, 1992.
79. Tomberlin JK, Halperin EC, Kusin P, Leopold K, Bentel G, George S, Powers M, Wolfe W. Endobronchial interstitial AU-198 implantation in the treatment of recurrent bronchogenic carcinoma. J Surg Oncol, 49:213-219, 1992.
80. Bruggers CS, Friedman HS, Fuller G, Tien R, Marks L, Halperin EC, Hockenberger B, Oakes WJ. Comparison of serial PET and MRI scans in a pediatric patient with a brainstem glioma. Med and Pediatric Oncol, 21:301-306, 1993.
81. Kligerman AD, Bryant MF, Doerr CL, Halperin EC, Kwanyuen P, Sontag, MR, Erexson GL. Interspecies cytogenetic comparisons: Studies with x-radiation and bleomycin sulfate. Environ and Molec Mutagenesis, 19:235-243, 1992.
82. Mallik RK, Fuller GN, Oakes WJ, Tien R, Hockenberger B, Freidman HS, Halperin EC. Clinical conference. Back pain and paraplegia in a 15 year old boy. J of Pediatrics, 121:652-658, 1992.
83. Arora V, Weeks K, Halperin EC, Dutton JJ. Influence of coralline hydroxyapatite used as an ocular implant upon the dose distribution of external beam photon radiation therapy. Ophthalmology, 99(3):380-382, 1992.
84. Gaspar L, Fisher BJ, Macdonald DR, LeBer DV, Halperin EC, Schold Jr., SC, Cairncross JG. Supratentorial malignant glioma: Patterns of recurrence and implications for external beam local treatment. Int J Rad Onc Biol Phys, 24:55-57, 1992.
85. Marks LB, Halperin EC, Prosnitz LR, Ross M, Vredenburg JJ, Rosner GL, Peters W. Post-mastectomy radiotherapy following adjuvant chemotherapy and autologous bone marrow transplantation for breast cancer patients with greater than or equal to 10 positive axillary lymph nodes. Int J Rad Onc Biol Phys, 23:1021-1026, 1992.
86. Halperin EC. Multiple fraction-per-day external beam radiotherapy for adults with supratentorial malignant gliomas. J Neuro-Oncol, 14:255-262, 1992.
87. Halperin EC. The journal goes after a big scoop: The deputy editor tries on a new hat. N C Med J, 53(6):305-307, 1992.
88. Halperin EC, Scott J, George SL. Multiple authorship in two English language journals in radiation oncology. Acad Med, 67(12):850-855, 1992.
89. Halperin EC, Gaspar L, George S, Darr D, Pinnell S. A double-blind, randomized, prospective trial to evaluate topical vitamin C solution for the prevention of radiation dermatitis. Int J Rad Onc Biol Phys, 26:413-416, 1993.
90. Halperin EC, Gaspar L, Imperato J, Salter M, Herndon J, Dowling S. An analysis of radiotherapy data from the CNS Cancer Consortium's randomized prospective trial comparing AZQ to BCNU in the treatment of patients with primary malignant brain tumors. Am J Clin Onc, 16(4):277-283, 1993.
91. Gockerman J, Halperin EC, Hendrix B. Physician-assisted suicide and advance directives concerning life support. NC Med J, 54:312-320, 1993.
92. Halperin EC. Politics and Medicine. The journal interviews the candidates for Governor. NC Med J, 53(10):538-545, 1992.
93. Halperin EC, Friedman H, Schold Jr., SC, Fuchs HE, Oakes WJ, Hockenberger B, Burger PC. Surgery, hyperfractionated craniospinal irradiation, and adjuvant chemotherapy in the management of supratentorial embryonal neuroepithelial neoplasms in children. Surg Neurol, 40:278-283, 1993.
94. Halperin EC. Concerning the inferior portion of the spinal radiotherapy field for malignancies which disseminate via the cerebrospinal fluid. Int J Rad Oncol Biol Phys, 26:357-362, 1993.
95. Gaspar, LE., Fisher, BJ, Macdonald DR, LeBer DV, Halperin EC, Schold Jr., SC, Cairncross, JG. Malignant glioma - timing of response to radiation therapy. Int J Rad Oncol Biol Phys, 25:877-879, 1993.
96. Donnal J, Halperin EC, Friedman HS, Boyko CB. Subfrontal recurrence of medulloblastoma. Am J Neuro Rad, 13:1617-1618, 1992.
97. Nelson SC, Friedman HS, Oakes WJ, Halperin EC, Tien R, Fuller GN, Hockengerger B, Scroggs MW, Mancino M, Kurtzberg J, Buckley EG. Successful therapy for trilateral retinoblastoma. Am J Ophthal, 114:23-29, 1992.
98. Gravatt LC, Chaffee S, Hebert ME, Halperin EC, Friedman HS, Kurtzberg J. Efficacy and toxicity of a-ß-D-arabinofuranosylguanine (ara-G) as an agent to purge malignant T-cells from murine bone marrow: Application to an in vivo T-leukemia model. Leukemia, 7(8):1261-1267, 1993.
99. Acker JC, Bossen EH, Halperin EC. The management of desmoid tumors. Int J Rad Oncol Biol Phys, 26:851-858, 1993.
100. Bentel GC, Halperin EC, Buckley EG. Iodine-125 embedded in an orbital prosthesis for re-treatment of recurrent retinoblastoma. Med Dosimetry, 18:1-5, 1993.
101. Schold SC Jr, Herndon JE, Burger PC, Halperin EC, Vick NA, Cairncross JG, MacDonald DR, Dropcho EJ, Morawetz R, Bigner DD, Mahaley MS Jr. Randomized comparison of diaziquone and carmustine in the treatment of adults with anaplastic glioma. J Clin Oncol, 11(1):77-83, 1993.
102. Freeman CR, Krischer JP, Sanford RA, Cohen ME, Burger PC, del Carpio R, Halperin EC, Munoz L, Friedman HS, Kun LE. Final results of the study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: A pediatric oncology group study. Int J Rad Oncol Biol Phys, 27:197-206, 1993.
103. Moghrabi A, Friedman HS, McLendon R, Hockenberger B, Tien RD, Halperin EC, Oakes WJ. Arteriovenous malformation mimicking recurrent medulloblastoma. Med Ped Oncol, 22:140-143, 1994.
104. Marks LB, Halperin EC. The use of G-CSF during craniospinal irradiation. Int J Rad Oncol Biol Phys, 26:905-906, 1993.
105. LaChance DH, Brizel DM, Gockerman JP, Halperin EC, Burger PC, Boyko OB, Brown MT, Schold Jr., SC. Cyclophosphamide, doxorubicin, vincristine and prednisone for primary central nervous system lymphoma: Short duration response, multi-focal intracerebral recurrence preceding radiotherapy. Neurology, 44:1721-1727, 1994.
106. Hebert ME, Halperin EC, Oakes WJ, Boyko OB. Multiple fraction-per-day radiotherapy for patients with brain stem tumors. J Neuro-Oncology, 17:131-138, 1993.
107. Bauman GS, Gaspar LE, Fisher BJ, Halperin EC, Macdonald DR, Cairncross JG. A prospective study of short course radiotherapy in poor prognosis glioblastoma multiforme. Int J Rad Oncol Biol Phys, 29(4):835-840, 1994.
108. Halperin EC, Godwin B, Harper RL. Racial stereotypes and campus police composites: Taking a second look. Black Issues in Higher Educ, 10:34-35, 1993.
109. Halperin EC. Eureka! It's a negative study! NC Med J, 55:68-69, 1994.
110. Halperin EC, Sontag MR. Special Topic Overview. Techniques of experimental animal radiotherapy. Laboratory Animal Sci, 44(5):417-423, 1994.
111. Halperin EC. The Journal interviews Lieutenant Governor Dennis Wicker. NC Med J, 55(5):194-196, 1994.
112. Nashold JRB, Oakes WJ, Friedman HS, Halperin EC, Soo M, Hockenberger B, Fuller GN, Tien R. Management of pineal non-germinoma germ cell tumor with residual teratoma and normal alpha-fetoprotein. Med Ped Oncol, 22:137-139, 1994.
113. Halperin EC. Is tenure irrelevant for academic clinicians? South Med J, 88(11):1099-1106, 1995.
114. Halperin EC. Family business. N.C. Med. J, 55(10):494-5, 1994.
115. Osumi AK, Mclendon RE, Tien RD, Friedman HS, Graham M, Hockenberger B, Halperin EC, Oakes WJ. Well differentiated astrocytoma occurring nine years after radiation for medulloblastoma. Clin Neuropathology, 13(5):281-5, 1994.
116. Halperin EC. Oral contraceptives as an over-the-counter medication. NC Med J, 55(5): 183-6, 1994.
117. Halperin EC. Malignant gliomas in older adults with poor prognostic signs: Getting nowhere and taking a long time to do it. Oncology, 9:299-243, 1995.
118. Halperin EC. The North Carolina Mutual Life Insurance Company, Dr. Clyde Henry Donnell, and the health education of blacks. NC Med J, 56(11):570-574, 1995.
119. Halperin EC, Byyny RL, Moore S, Morahan PS. What medical schools and universities can learn from one another. Academic Med, 70(10):879-883, 1995.
120. Halperin EC, Herndon J, Schold SC Jr., Brown M, Vick N, Cairncross JG, Macdonald DR, Gaspar L, Fischer B, Dropcho E, Rosenfeld S, Morowitz R, Piepmeier J, Hait W, Byrne T, Salter M, Imperato J, Khandekar J, Paleologos N, Burger P, Bentel GC, Friedman A. A Phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. Int J Rad Oncol Biol Phys, 34(4):793-802, 1996.
121. Yamaguchi Y, Halperin EC, Mori K, Bollinger RR, Ogawa M. Recipient Kupffer cell influx into xenografted liver. Dig Dis Scien, 40(3):548-551, 1995.
122. Halperin EC. Urinate in the cup, doctor. NC Med J, 56(6):274-278, 1995.
123. Halperin EC (editor). Physicians' roundtable: Three rear ends on the beach: Debating the ethics of medical advertising. NC Med J, 56(8):402-405, 1995.
124. Halperin EC, Samulski T, Oakes WJ, Friedman HS. Fabrication and testing of a device capable of reducing the incidence of ventricular shunt prompted metastases. J Neuro-Onc, 27:39-46, 1996.
125. Graham ML. Rosse WF. Halperin EC. Miller CR. Ware RE. Resolution of Budd-Chiari syndrome following bone marrow transplantation for paroxysmal nocturnal haemoglobinuria. British J of Haematology, 92(3):707-10, 1996.
126. Halperin EC. Why is female sex an independent predictor of shortened overall survival after proton/photon radiation therapy for skull based chordomas? Int J Rad Oncol Biol Phys, 38(2):225-30, 1997.
127. Halperin EC. Impact of radiation technique upon the outcome of treatment for medulloblastoma. Int J Rad Oncol Biol Phys, 36(1):233-239, 1996.
128. Halperin EC. Long term results of therapy for stage C neuroblastoma. J Surg Oncol, 63:172-178, 1996.
129. Halperin EC, Friedman HS. Is there a correlation between duration of presenting symptoms and stage of medulloblastoma at the time of diagnosis? Cancer, 78:874-880, 1996.
130. Kurtzberg J, Laughlin M, Graham ML, Smith C, Olson JF, Halperin EC, Ciocci G, Carrier C, Stevens CE, Rubinstein P. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Eng J Med, 335(3):157-166, 1996.
131. Merrill PT, Buckley EG, Halperin EC. New and recurrent tumors in germinal retinoblastoma: Is there a treatment effect? Ophthalmic Genetics, 17(3):115-118, 1996.
132. Constine LS, Marcus RB Jr., Halperin EC. The future of therapy for childhood rhabdomyosarcoma: clues from molecular biology. Int J Rad Oncol Biol Phys, 32(4):1245-1249, 1995.
133. Halperin EC. Why a special issue of the North Carolina Medical Journal on Gay and Lesbian medicine? NC Med J, 58(2):90-91, 1997.
134. Halperin EC. Broadwater GSL. Are there gender biases in standardized tests of radiation oncology knowledge? J Clinical Oncology, 15(7):2722-7, Jul.1997.
135. Strother D, van Hoff J, Rao PV, Smith EI, Shamberger R, Halperin EC, Murray KJ, Castleberry RP. Event-free survival of children with biologically favourable neuroblastoma based on degree of initial tumor resection: results from the Pediatric Oncology Group. Europ J Cancer, 33(12):2121-5, 1997.
136. Halperin EC. Children are not supposed to die. Combined Pediatric and Radiation Oncology Grand Rounds addresses severe illness and death. NCMJ 58(6), November/December 1997.
137. Halperin EC. Let's abolish the office of alternative medicine of the national institutes of health. NC Med J, 59(1):21-23, 1998.
138. Marks LB, Peterson BL, Halperin EC. The impact of competing risks on actuarial estimates of local control in patients with brain metastases. Radiosurgery, 2:86-93. (Editor: Kondziolka, D. Basel: Karger).
139. Drayer JA, Marks LB, Bentel G, Halperin EC. Defining the superior border of posterior fossa radiation treatment fields. Int J Rad Oncol Biol Phys, 41(3):625-629, 1998.
140. Graham ML, Asselin BL, Herndon JE 2nd, Casey JR, Chaffee S, Ciocci GH, Daeschner CW, Davis AR, Gold S, Halperin EC, Laughlin MJ, Martin PL, Olson JF, Kurtzberg J. Toxicity, pharmacology and feasibility of administration of PEG-L-asparaginase as consolidation therapy in patients undergoing bone marrow transplantation for acute lymphoblastic leukemia. Bone Marrow Trans, 21:879-885, 1998.
141. Maguire PD, Clough R, Friedman AH, Halperin EC. Fractionated external beam radiation therapy for meningiomas of the cavernous sinus. Int J Rad Oncol Biol Phys, 44(1):75-80, 1999.
142. Fortney JT, Halperin EC, Hertz CM, Schulman SR. Anesthesia for pediatric external beam radiation therapy. Int J Rad Oncol Biol Phys, 44(3):587-91, 1999.
143. Halperin EC. Publish or perish-and bankrupt. The medical library while you're at it. Academic Medicine, 74(5):470-472, 1999.
144. Halperin EC. The North Carolina Medical Journal finds itself in the vanguard of progressive medical journalism. Or, The deputy editor finds his fifteen minutes of fame. NC Med J, 60(3):138-9, 1999.
145. Halperin EC. Radiation therapy and xenotransplantation. Science & Medicine, 6:52-61, 1999.
146. Halperin EC. Neonatal neoplasms. Int J Rad Oncol Biol Phys, 47(1):171-178, 2000.
147. DeBacker CM, Dutton JJ, Proia A, Halperin EC, Wagle N, Holck DEE. The influence of hyperbaric oxygen therapy and irradiation on hydroxyapatite ocular implant exposure and fibrovascular ingrowth in New Zealand white rabbits. Opthalmic Plastic and Reconstructive Surgery, 15(6):412-419, 1999.
148. Halperin EC. Overpriced high technology in radiation oncology. Int J Rad Oncol Biol Phys, 48(4):917-918, 2000.
149. Halperin EC. Grievances against physicians: 11 year’s experience of a medical society grievance committee. Western Med J, 173:235-238, 2000.
150. Halperin EC. Francis Henry Williams: A completely efficient life. NC Med J, 61:199-202, 2000.
151. Halperin EC, Watson DM, George SL. Duration of symptoms prior to diagnosis is inversely related to presenting stage of medulloblastoma Cancer, 91(8):1444-1450, 2001.
152. Halperin EC. The Jewish Problem in U.S. Medical Education, 1920-1950. Journal of the History of Medicine and Allied Sciences, 56:140-167, 2001.
153. Halperin EC. Non-human to human organ transplantation: Its biologic basis and a potential role for radiation therapy. Int J Cancer (Rad Oncol Inves), 96:76-89, 2001.
154. Halperin EC. Should academic physicians conduct clinical trials of the efficacy of intercessory prayer? Academic Medicine, 76(8):791-797, 2001.
155. Wenzel CT, Halperin EC, Fisher SR. Second malignant neoplasms of the head and neck in survivors of retinoblastoma. Ear, Nose & Throat Journal, 80:106-112, 2001.
156. Hutchinson P, Halperin EC. The hidden persuaders: Subtle advertising in radiation oncology. Int. J Rad Oncol Biol Phys, 54(4):989-991, 2002.
157. Halperin EC, Laurie F, Fitzgerald TJ. An evaluation of the relationship between the quality of prophylactic cranial radiation therapy in childhood acute leukemia and institutional experience: A quality assurance review center-pediatric oncology group study. Int J Rad Oncol Biol Phys, 53(4):1001-1004, 2002.
158. Kang, SH, Kirkpatrick J, Halperin EC. Low-dose radiation for post-transplant lymphoproliferative disorder. American J Clin Oncol, 26(2):210-214, 2003.
159. Halperin EC. Cancer Management Controversy. The Corporate Presence at Oncology Meetings. Am J Clin Oncol, 25(5):535-536, 2002.
Contact InfoUniversity Radiotherapy Associates, Inc.
529 S. Jackson St.
Louisville, KY 40202
Phone: 502-562-4360
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