Brad K. Rodu, DDS
Research Program
Prevention & Control
Education
Ohio State University, Columbus, Ohio, Pre-Dentistry, 1972-1974.
D.D.S., Ohio State University, Columbus, Ohio, Dentistry, 1974-1977.
Resident, Ohio State University, Columbus, Ohio, Oral Pathology, 1977-1978.
Resident, Emory University, Atlanta, Georgia, Oral Pathology, 1978-1979.
Research and Professional Experience
1979-1981
NCI Clinical Associate in Oncology
ACS Clinical Fellowship
University of Alabama at Birmingham
1981-1985
Assistant Professor, Department of Pathology; Associate Scientist, Comprehensive Cancer Center, University of Alabama at Birmingham
1981-1996
Director, Dental Oncology Service, Comprehensive Cancer Center, University of Alabama at Birmingham
1982-2005
Medical and Dental Staff, Pathology Service, University of Alabama at Birmingham
1984-2005
Assistant Professor, Department of Radiation Oncology, University of Alabama at Birmingham
1985-1997
Associate Professor, Department of Pathology; Scientist, Comprehensive Cancer Center, University of Alabama at Birmingham
1990-1996
Director, Oral Pathology Graduate Program, University of Alabama at Birmingham
1991-2005
Professor of Dentistry, School of Dentistry, University of Alabama at Birmingham
1997-2005
Professor, Department of Pathology; Senior Scientist, Comprehensive Cancer Center, University of Alabama at Birmingham
2005-Present
Professor, Department of Medicine, University of Louisville
2005-Present
Senior Scientist, James Graham Brown Cancer Center, University of Louisville
Research Interest
Dr. Rodu’s research focus has been on tobacco harm reduction, involving the substitution of safer tobacco products for smokers who are unable or unwilling to quit smoking with conventional cessation methods. His published research includes epidemiologic models regarding life expectancy of tobacco users, prevalence studies of tobacco use and adverse health consequences in Sweden, and laboratory analyses of tobacco products. For more information about this research, visit www.smokersonly.org
Publications
Ebbinghaus SW, Gee JE, Rodu B, Mayfield CA, Sanders G, Miller DM. Triplex formation inhibits HER-2/neu transcription in vitro. J Clin Invest 92:2433-9, 1993.
Campbell VW, Davin D, Thomas S, Jones DJ, Roesel J, Tran-Paterson R, Mayfield CA, Rodu B, et al. The G-C specific DNA binding drug, mithramycin, selectively inhibits transcription of the c-myc and c-ha-ras genes in regenerating liver. Am J Med Sci 307:167-72, 1994.
Mayfield C, Ebbinghaus S, Gee J, Jones D, Rodu B, Squibb M, Miller D. Triplex formation by the human Ha-ras promoter inhibits Sp1 binding and in vitro transcription. J Biol Chem 269:18232-8, 1994.
Tilashalski K, Rodu B, Mayfield C. Assessing the nicotine content of smokeless tobacco products. JADA 125:590-4, 1994.
Rodu B. An alternative approach to smoking control. Am J Med Sci 308:32-4, 1994.
Rodu B, Cole P. Tobacco-related mortality. Nature 370:184, 1994.
Allen CM, Damm D, Neville B, Rodu B, et al. Necrosis in benign salivary gland neoplasms: Not necessarily a sign of malignant transformation. Oral Surg 78:455-61, 1994.
Rodu B. Oral pathology. In: Barnes CM, Waring MB (eds), Review of Dental Hygiene. Appleton and Lange, 1994.
Garver RI Jr, Goldsmith KT, Rodu B, Hu P-C, Sorscher EJ, Curiel DT. Strategy for achieving selective killing of carcinomas. Gene Therap 1:46-50, 1994.
Rodu B, Cole P. Excess mortality in smokeless tobacco users not meaningful. Am J Public Health 85:118, 1995.
Vigneswaran N, Tilashalski K, Rodu B, Cole P. Tobacco use and cancer: A reappraisal. Oral Surg 80:178-82, 1995.
Tilashalski K, Lozano K, Rodu B. Modified tobacco use as a risk-reduction strategy. J Psychoactive Drugs 27:173-5, 1995.
Rodu B. For Smokers Only: How Smokeless Tobacco Can Save Your Life. Salzburger and Graham Publishing, Ltd., NY, 1995.
Rodu B. Smokeless tobacco for smoking cessation: A practical harm reduction strategy. Ohio Dent J 70:6, 1996.
Rodu B, Cole P. The rewards of smoking cessation. Epidemiology 7:111-2, 1996.
Vigneswaran N, Mayfield CA, Rodu B. Influence of GC and AT specific DNA minor groove binding drugs on intermolecular triplex formation in the human c-Ki-ras promoter. Biochemistry 35:1106-14, 1996.
Cole P, Rodu B. Declining cancer mortality in the United States. Cancer 78:2045-8, 1996.
Meredith R, Salter M, Kim R, Spencer S, Weppelman B, Rodu B, Smith J, Lee J. Sucralfate for radiation mucositis: Results of a double-blind randomized trial. Int J Rad Onc Biol Phys 37:275-9, 1997.
Vigneswaran N, Tilashalski KR, Peters GE, Reddy VV, Rodu BK. Ulcerated tumor mass involving the right base of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontics 84:461-4, 1997.
Sartin EA, Weiss RC, Baird AN, Baird DK, Spano JS, Rodu B, Vigneswaran N. Ameloblastic fibrosarcoma in a bull. J Comp Path 118:51-5, 1998.
Tilashalski K, Rodu B, Cole P. A pilot study of smokeless tobacco in smoking