Kara J. Sedoris, Ph.D.

Instructor, Department of Medicine; Assistant Scientist, James Graham Brown Cancer Center

Research Program
Molecular Targets

Education
B,A, Ohio Wesleyan University, 2000
M.S., Ph.D., University of Louisville, Physiology/Biophysics, 2005
Postdoctoral Fellow, University of Louisville, Cancer Biology, 2005-2009

Research and Professional Experience
1996-1999
Research Assistant in Botany/Microbiology, Ohio Wesleyan University

1999-2000
Summer Research Assistant, Kentucky Lions Eye Center, University of Louisville

2009-present
Instructor, Department of Medicine, University of Louisville

2009-present
Assistant Scientist, James Graham Brown Cancer Center

Selected Awards and Professional Honors
2004
Research!Louisville, 1st Place in Research Competition, University of Louisville

2006
Southern Society for Clinical Investigation, 3rd Place - Research Competition, Atlanta, GA

2006-present
Associate Member, American Association for Cancer Research (AACR)

Publications

Ovechkin AV, Lominadze D, Sedoris KC, Gozal E, Robinson TW, Roberts AM. Inhibition of inducible nitric oxide synthase attenuates platelet adhesion in subpleural arterioles caused by lung reperfusion in rabbits. J Appl Physiol 99:2423-32, 2005

Tyagi N, Sedoris KC, Ovechkin AV, Moshal KS, Tyagi SC. Mechanisms of homocysteine-induced oxidative stress of oxidative stress. Am J Physiol Heart Circ Physiol 289:H2649-56, 2005

Ovechkin AV, Lominadze D, Sedoris KC, Robinson TW, Tyagi SC, Roberts AM. Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions. Arch Physiol Biochem 13:1-12, 2007

Sedoris KC, Thomas SD, Miller DM. C-Myc promoter binding protein regulates the cellular response to an altered glucose concentration. Biochemistry 46:8659-68, 2007

Sedoris KC, Ovechkin AV, Gozal E, Roberts AM. Differential effects of nitric oxide synthesis on pulmonary vascular function during lung ischemia-reperfusion injury. Arch Physiol Biochem 115(1):34-46, 2009