Shared Facilities: Biophysics Core
In addition to structure determination of isolated components
and complexes, it is essential to determine the energetics and
kinetics of the interactions, and changes in physical properties
of the components on forming the complexes. To this end, a biophysics
core laboratory has being established at BCC where researchers
can measure functional properties of their purified systems. This
is achieved using a variety of biophysical methods including calorimetry,
optical spectroscopy such as fluorescence and circular dichroism,
surface plasmon resonance, rapid reaction kinetics and hydrodynamic
techniques (Chaires).